How-To·6 min read·January 28, 2025
Injection Techniques: Subcutaneous vs Intramuscular
Most peptides are injected subcutaneously, but some protocols call for IM. Here's how to do both correctly.
Subcutaneous (SubQ) — the default
Used for: most peptides (BPC-157, GLP-1s, GHK-Cu, growth hormone secretagogues)
Where: belly fat (1-2 inches from navel), love handles, back of arm, thigh
Needle: 29-31g insulin syringe, 1/2" length
Technique:
- Pinch 1-2 inches of skin/fat
- Insert needle at 90° (or 45° if very lean)
- Inject slowly over 2-3 seconds
- Hold for 5 seconds before withdrawing
Intramuscular (IM)
Used for: some longer-acting compounds, certain healing protocols
Where: deltoid (shoulder), vastus lateralis (outer thigh), glute
Needle: 23-25g, 1" to 1.5" length
Technique:
- Stretch skin flat (don't pinch)
- Insert needle at 90° in one quick motion
- Aspirate (pull back slightly) to ensure no blood return
- Inject slowly
- Withdraw and apply pressure
Rotation matters
Always rotate injection sites. Repeated injections in the same spot cause scar tissue, lumps, and reduced absorption.