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Compounds·6 min read·February 15, 2025

GHK-Cu: Skin, Hair, and Beyond

The copper peptide that started in cosmetics has serious systemic potential. Here's what the science shows.

What is GHK-Cu?

GHK-Cu is a small peptide (just 3 amino acids) bound to copper. It's naturally present in human plasma but declines sharply with age — by your 60s, levels are about a third of what they were at 20.

What it does

  • Stimulates collagen and elastin production
  • Activates wound healing genes
  • Reduces inflammation
  • Promotes hair growth (especially when applied topically to the scalp)
  • Antioxidant activity

How it's used

Topical

The most common form. Used in serums and creams for anti-aging and hair growth. Apply to clean skin or scalp daily.

Subcutaneous injection

Less common but research suggests systemic benefits — improved sleep, recovery, and even mood. Typical research doses: 1-3 mg/day.

Combining GHK-Cu

Often blended with BPC-157 and TB-500 (GLOW blend) for full-spectrum healing and skin benefits.

Things to watch

  • The blue color is normal (it's copper)
  • Don't take orally — it's destroyed in the gut
  • Avoid combining with high-dose vitamin C topically (can deactivate the copper)